Respiratory Translational Research Scientist
Job Description #1! That's the ranking that Fast Company gave Novartis in their 2018 list of 'The World's Most Innovative Companies'. The Novartis Institutes for BioMedical Research (NIBR) is the innovation engine of Novartis. We collaborate across scientific and organization boundaries, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.
Millions of people die from chronic lung diseases each year. Translational scientists at the Novartis Institutes for BioMedical Research seek to better understand chronic diseases and ultimately discover and develop transformative new medicines. We are seeking a motivated scientist to join the Disease Area translational group, who will be part of a team working to understand the genetic and molecular underpinnings of chronic lung disease by developing translatable in-vitro and ex-vivo assays for target discovery and validation and contributing to the establishment of a biorepository of human lung tissues for use in assay development and target validation.
The ideal candidate for this position has strong skills in cell and molecular biology, with experience developing in vitro/ex- vivo models for target validation. They will have a proven track record of independent work and creativity, and a history of success in cross-functional teams.
If you have collaborative nature, passion for understanding human data to inform future assays, dedication to teamwork across an organization and exceptional organizational skills, we invite you to apply.
Your responsibilities include, but are not limited to:
- Acquire, prepare and process human tissues (eg. lung) to expand biorepository efforts
- Perform purification and culture of primary human cell types
- Participate in complex assay development for target Identification/validation and for testing therapeutic efficacy of compounds at different stages
- Collaborate while working in a matrix environment to support drug discovery projects within the respiratory therapeutic area
- Perform data analysis and keep excellent laboratory, data recording and documentation practices
- Present plan/results/next steps in lab and department meetings
- The candidate may participate in alliances with external partners at top healthcare institutions, with the opportunity to publish your work EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Minimum requirements What you will bring to the role:
- BSc or MSc in cell biology, molecular biology, immunology, or other life science field with a minimum of 3-5 years related laboratory experience in an academic or industrial drug discovery setting
- Prior experience in isolation and culture of primary human cells
- Experience in a range of laboratory techniques including microscopy, RNA isolation, qPCR and Western blotting.
- Detailed-oriented, excellent record keeping and organizational skills.
- Flexibility and aptitude for learning, with a passion to drive excellent science
- A great teammate with a desire to work in a collaborative environment. The candidate will work both independently and as part of an interdisciplinary team of translational research/medical scientists, biologists and computational scientists
- Handle multiple tasks simultaneously and work to help create solutions and troubleshoot problems as they emerge
- Strong written and verbal communication skills
Desirable skills include, but not limited to:
- Respiratory disease biology knowledge (COPD, IPF, Asthma, Cystic fibrosis)
- Experience in CRISPR-CAS9, SiRNA or any other gene editing technologies
Why Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we're proud of this, we know there is so much more we could do to help improve and extend people's lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Work Location Cambridge, MA Company/Legal Entity NIBRI Functional Area Research & Development
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Novartis Group Companies
June 20, 2022