Specialist- Craik Lab

Specialist Position - Craik Lab

Department of Pharmaceutical Chemistry

University of California, San Francisco

The Department of Pharmaceutical Chemistry is seeking a Junior/Assistant/Associate/Full Specialist in the Craik Lab. The Craik lab (https://pharm.ucsf.edu/craik) does chemical biology research with the intention of finding potent and specific enzyme inhibitors by studying the substrate specificity and structure of the enzymes. The enzymes are also used in high throughput screens to identify small molecule substrates and inhibitors whose binding modes are studied using biophysical methods. In addition, the lab identifies recombinant antibodies that bind to conformational states of enzyme, membrane proteins, protein complexes and other challenging targets. This involves phage display, cloning, purification, and analysis of protein homologues found in various organisms. The enzymes are also used in high throughput screens to identify small molecule substrates and inhibitors whose binding modes are studied using spectroscopy.

This position provides support to the research by assisting and carrying our research projects involving phage display, protein expression & purification and subsequent biochemical analysis. The Specialist will also provide support for lab maintenance and organization.

Required Qualifications:

* Specialists appointed at the Junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of relevant research experience

* Specialists appointed at the Assistant rank must possess a master's degree (or equivalent degree) or at least five years of experience in the relevant specialization

* Specialists appointed at the Associate rank must possess a master's degree (or equivalent degree) or five to ten years of experience in the relevant specialization

* Specialists appointed at the full rank must possess a terminal degree (or equivalent degree) or ten or more years of experience in the relevant specialization

* Excellent verbal and written communication skills and ability to interact productively with lab and campus personnel

* Ability to manage multiple tasks effectively

* Knowledge of computer systems and software

* Ability to monitor spending and manage budgets related to ordering supplies for the lab

* Candidates must meet the required qualifications at the time of appointment. Candidate's CV must state qualifications (or if pending) upon submission.

Preferred Qualifications:

* Experience with biochemical methods including phage display, protein expression and purification, cloning, kinetic analysis and biophysical characterization using biolayer interferometry and surface plasmon resonance. Experience with peptide synthesis and characterization is preferred.

Please apply online at https://aprecruit.ucsf.edu/JPF04276, with a CV, cover letter, and the contact information of 3 references.

See Table 24B (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t24-b.pdf) for the salary range for this position. A reasonable estimate for this position is $49,000-$173,900.

• 3 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.